NAD+ Explained
Dr. Steven E. Bennett Dr. Steven E. Bennett

NAD+ Explained

Unfortunately, as we age, our supply of NAD+ naturally disappears. By age 40, most people have lost about half of their youthful levels, and by age 60, they may have only 20% left. This happens because certain enzymes in the body start to "steal" and consume NAD+ much faster than we can replace it, usually to deal with rising inflammation or to try and fix mounting DNA damage. As NAD+ is used up by these "thieves," there is not enough left to run your power plants or fuel your repair crews. Begins Here

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Metabolic Preservation Strategies: A Clinical Framework for Resistance Training and Nutrient Timing in GLP-1 Therapy
Dr. Steven E. Bennett Dr. Steven E. Bennett

Metabolic Preservation Strategies: A Clinical Framework for Resistance Training and Nutrient Timing in GLP-1 Therapy

Emerging data indicate that 20% to 50% of total weight loss during GLP-1 RA therapy may consist of lean mass, with some cohorts showing muscle loss as high as 60%. This reduction in skeletal muscle integrity presents a significant risk for sarcopenic obesity, metabolic rate depression, and decreased functional independence.

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The Longevity Coenzyme: Clinical Efficacy of Subcutaneous Nicotinamide Adenine Dinucleotide in Addressing Age-Related Pathophysiology and Metabolic Decline
Dr. Steven E. Bennett Dr. Steven E. Bennett

The Longevity Coenzyme: Clinical Efficacy of Subcutaneous Nicotinamide Adenine Dinucleotide in Addressing Age-Related Pathophysiology and Metabolic Decline

Subcutaneous (SC) injections have emerged as a superior modality for achieving therapeutic concentrations while mitigating the metabolic bottlenecks associated with oral ingestion and the systemic side effects inherent to rapid intravenous delivery. This analysis explores the mechanistic underpinnings of NAD+ therapy, the clinical superiority of the subcutaneous route, and the synergistic integration of NAD+ restoration with emerging medical technologies and supportive measures in managing the hallmarks of aging.

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